Fig. 2

Patient example of the longitudinal changes in SRF, IRF, PED, TF volume. Multimodal imaging and fluid analysis obtained from the Discovery® platform (RetinAI Discovery Layer and Fluid Segmentation and Biomarker Processor, Ikerian AG, Switzerland). (A-E-I) Infrared image respectively at baseline 1-month and 3-month follow up. (B-F-J) Multicolor imaging respectively at baseline 1-month and 3-month follow up. (C-G-K) Autofluorescence, respectively at baseline 1-month and 3-month follow up. (D-H-L) OCT scan segmented with AI software RetinAI (segmentation in violet indicates PED, light violet SRF, light blue IRF), respectively at baseline 1-month and 3-month follow up showing the early drying effect after IVT aflibercept 8 mg loading dose. SHRM (white star in D) resolution over the 3-month follow up can be observed