Fig. 2

Spectral domain optical coherence tomography (SD-OCT) scans of left eye of a male infant born at age of 28 weeks with 1200 gm admitted in NICU for 70 days and presented at age of 36 weeks with Type 1 ROP (ROP zone II, stage 3, and plus disease) (A) OCT image at time of presentation with macular edema (ME) and CFT 380 µm and B OCT image at one month showing resolution of ME (CFT 209 µm) with ORL thickening and differentiation but with delayed IRL differentiation. OCT images of right eye of a female infant born at age of 28 weeks with 1100 gm admitted in NICU for 52 days on ventilator and presented at age of 38 weeks with Type 1 ROP (ROP zone II, stage 3, and plus disease), C OCT image at time of presentation with macular edema (ME) and CFT 318 µm and D OCT image at one month showing resolution of ME (CFT 177 µm) with ORL thickening and appearance of IS/OS junction and IRL differentiation. OCT images of left eye of a female infant born at age of 28 weeks with 1800 gm admitted in NICU for 12 days and presented at age of 33 weeks with Type 1 ROP (ROP zone II, stage 2, and plus disease), E OCT image at time of presentation with macular edema (ME) and CFT 461 µm and F OCT image at one month showing worsening of ME (CFT 520 µm) with poor retinal layer differentiation. Similarly, OCT images of right eye of a female infant born at age of 32 weeks with 1140 gm admitted in NICU for 46 days with history of sepsis, presented at age of 38 weeks with aggressive ROP, G OCT image at time of presentation with macular edema (ME) and CFT 354 µm and H OCT image at one month showing worsening of ME (CFT 483 µm) with poor retinal layer differentiation