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Table 3 The baseline optical coherence tomography markers of patients with vision loss of more than 15 ETDRS letters from baseline to months 3 and 12

From: Predictive value of different baseline optical coherence tomography biomarkers for visual acuity changes in neovascular age-related macular degeneration

 

Vision loss in month 3

Vision loss in month 12

15 ≥ ETDRS letters

N (%)

15 < ETDRS letters

N (%)

P†

15 ≥ ETDRS letters

N (%)

15 < ETDRS letters

N (%)

P†

SIPED

      

 No

31 (96.9%)

1 (3.1%)

0.837

29 (90.6%)

3 (9.4%)

0.828

 Yes

48 (96.0%)

2 (4.0%)

 

46 (92.0%)

4 (8.0%)

 

SHRM

      

 No

11 (91.7%)

1 (8.3%)

0.382

12 (100.0%)

0 (0.0%)

0.586

 Yes

68 (97.1%)

2 (2.9%)

 

63 (90.0%)

7 (10.0%)

 

SRF

      

 No

12 (92.3%)

1 (7.7%)

0.408

11 (84.6%)

2 (15.4%)

0.306

 Yes

67 (97.1%)

2 (2.9%)

 

64 (92.8%)

5 (7.2%)

 

IRF

      

 No

34 (100.0%)

0 (0.0%)

0.263

34 (100.0%)

0 (0.0%)

0.038

 Yes

45 (93.8%)

3 (6.3%)

 

41 (85.4%)

7 (14.6%)

 

HRF (subretinal)

      

 No

17 (94.4%)

1 (5.6%)

0.53

15 (83.3%)

3 (16.7%)

0.175

 Yes

62 (96.9%)

2 (3.1%)

 

60 (93.8%)

4 (6.3%)

 

HRF (intraretinal)

      

 No

20 (100.0%)

0 (0.0%)

0.573

20 (100.0%)

0 (0.0%)

0.186

 Yes

59 (95.2%)

3 (4.8%)

 

55 (88.7%)

7 (11.3%)

 

SDD

      

 No

64 (97.0%)

2 (3.0%)

0.483

61 (92.4%)

5 (7.6%)

0.618

 Yes

15 (93.8%)

1 (6.3%)

 

14 (87.5%)

2 (12.5%)

 

Pre-choroidal cleft

      

 No

76 (96.2%)

3 (3.8%)

>0.99

72 (91.1%)

7 (8.9%)

>0.99

 Yes

3 (100.0%)

0 (0.0%)

 

3 (100.0%)

0 (0.0%)

 
  1. †Based on GEE analysis. Bold values indicate statistically significant differences
  2. BCVA best-corrected visual acuity, SIPED shallow irregular pigment epithelial detachment, SHRM subretinal hyperreflective material, SRF subretinal fluid, IRF intraretinal fluid, HRF hyperreflective foci, SDD subretinal drusenoid deposit