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Table 4 Time trend of the AI-assisted Volumetric Analysis over the follow-up period through

From: Faricimab efficacy in type 1 macular neovascularization: AI-assisted quantification of pigment epithelium detachment (PED) volume reduction over 12 months in Naïve and switch eyes

Factors and categories

Mean

95%CL

Mean difference

95%CL

P-value

PED Volume (nL)

    

< 0.001*

Baseline

810

578/1041

0.0

(Ref.)

 

3-month

621

426/815

-189

-256/-122

 

6-month

642

438/845

-168

-235/-101

 

12-month

604

598/977

-206

-273/-138

 

SRF Volume (nL)

    

0.038*

Baseline

145.7

77.0/214.9

0.0

(Ref.)

 

3-month

21.1

5.01/37.1

-124.6

-176.8/-72.3

 

6-month

48.2

10.5/85.8

-97.55

-149.8/-45.3

 

12-month

9.74

1.35/18.1

-136.02

-188.3/-83.7

 

IRF Volume (nL)

    

< 0.001*

Baseline

27.8

11.4/44.2

0.0

(Ref.)

 

3-month

11.9

-0.7/24.7

-15.8

-28.1/-3.5

 

6-month

9.9

-0.4/20.2

-17.9

-30.1/-5.6

 

12-month

5.7

-01.5/12.9

-22.2

-34.3/-9.8

 
  1. Legenda – 95%CL: 95% confidence limits for means. Ref.: reference category; P-value: probability level derived from the likelihood ratio test applied to a random-effects linear model