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Table 2 Distribution of type 1 macular neovascularization exudative features according to Naïve and switch status

From: Faricimab efficacy in type 1 macular neovascularization: AI-assisted quantification of pigment epithelium detachment (PED) volume reduction over 12 months in Naïve and switch eyes

Exudative feature

Follow-up visit

Type 1 MNV

Total (%)

P-value

Switch (n = 52)

Naïve (n = 13)

N (%)

N (%)

SRF

Baseline

40 (76.9)

12 (92.3)

52 (80.0)

0.214

3-month

14 (26.9)

3 (23.1)

17(26.1)

0.777

6-month

17 (32.7)

2 (15.4)

19 (29.2)

0.219

12-month

6 (11.5)

0 (0.0)

6 (9.2)

0.198

IRF

Baseline

15 (28.8)

2 (15.3)

17 (26.1)

0.323

3-month

5 (9.6)

0 (0.0)

5 (7.7)

0.244

6-month

7 (13.7)

0 (0.0)

7 (10.8)

0.161

12-month

5 (9.6)

0 (0.0)

5 (7.6)

0.245

SHRM

Baseline

4 (7.6)

5 (38.4)

9 (13.8)

0.004*

3-month

3 (5.8)

0 (0.0)

3 (4.6)

0.375

6-month

4 (7.7)

0 (0.0)

4 (6.1)

0.296

12-month

3 (5.8)

0 (0.0)

3 (4.6)

0.373

Outward Exudation

Baseline

7 (13.4)

1 (7.6)

8 (15.4)

0.571

3-month

5 (9.6)

1 (7.7)

6 (9.2)

0.832

6-month

3 (5.8)

1 (7.7)

4 (6.1)

0.795

12-month

3 (5.8)

0 (0.0)

3 (4.6)

0.373

  1. Legenda – MNV: macular neovascularization; N/%: absolute/relative frequency; SRF: subretinal fluid, SHRM: subretinal hyperreflective material; IRF: intraretinal fluid; p-value: probability level derived by the chi-squared test