Fig. 2

Retinal fluid volumetric changes over 12 months in Switch (blue) and Naïve (orange) eyes treated with Faricimab. (A) Pigment epithelium detachment (PED) volume (nL). (B) Subretinal fluid (SRF) volume (nL). (C) Intraretinal fluid (IRF) volume (nL). Switch eyes exhibit higher baseline PED and IRF volumes, indicative of a chronic disease state. Conversely, Naïve patients show greater SRF volume at baseline. Both groups display a trend of reduction in fluids and PED volume, with a particularly notable early response observed at the 3-month follow-up, sustained at subsequent examinations