Table 1 Comparison of demographic, ocular, and OCT features in combined vs. sequential phacovitrectomy for Macular holes:
Variable | PVS group (n = 144) | CVS group (n = 39) | P value | |
|---|---|---|---|---|
Age (years) [Mean ± SD] | 68.35 ± 5.77 | 66.51 ± 5.501 | 0.059 | |
Gender (M: F) | 47:97 | 15:24 | 0.568 | |
Study eye (RE: LE) | 72:72 | 17:22 | 0.588 | |
Lens grade | Clear lens (n, %) | 0 (0) | 12 (31) | < 0.001 |
≤ NS 2 (n, %) | 118 (82) | 26 (67) | ||
> NS2 (n, %) | 12 (8) | 0 (0) | ||
PSC (n, %) | 30 (21) | 2 (5) | ||
CC (n, %) | 43 (30) | 1 (3) | ||
Pre-operative LogMAR VA | 0.868 ± 0.318 | 0.99 ± 0.339 | 0.043 | |
Pre-operative refractive error (SE) | 0.119 ± 1.350 | -0.232 ± 1.427 | 0.016 | |
Median OCT scan quality index (IQR) | 26 (22–29) | 27 (24–29) | 0.161 | |
OCT characteristics | Prefoveal PVD (n, %) | 113 (78) | 32 (82) | 0.824 |
ERM (n, %) | 39 (27) | 13 (33) | 0.432 | |
IRC (n, %) | 143 (99) | 38 (97) | 0.382 | |
Foveal RPE hyperreflectivity (n, %) | 132 (92) | 37 (95) | 0.737 | |
Outer basal diameter (microns) | 1090 ± 308.2 | 1069 ± 298.4 | 0.67 | |
Macular hole area (mm2) | 0.31 ± 0.111 | 0.292 ± 0.104 | 0.218 | |
HFF | 0.718 ± 0.147 | 0.678 ± 0.148 | 0.226 | |
MHI | 0.435 ± 0.143 | 0.432 ± 0.143 | 0.951 | |
THI | 0.242 ± 0.074 | 0.226 ± 0.067 | 0.142 | |
DHI | 0.474 ± 0.129 | 0.510 ± 0.143 | 0.275 | |
Median total follow-up duration (months) [IQR] | 16 (3–48) | 72 (30–84) | < 0.001 | |
MH status | Closed (n, %) | 123 (85) | 32 (82) | 0.619 |
Open (n, %) | 21 (15) | 7 (18) | ||
Post-operative LogMAR VA at the last follow-up visit | 0.596 ± 0.355 | 0.429 ± 0.419 | 0.001 | |
Post-operative refractive error (SE) | -0.437 ± 0.906 | -0.183 ± 1.228 | 0.191 | |
Change in the refractive before and after surgery (SE) | -0.555 ± 1.490 | 0.05 ± 1.729 | 0.04 | |