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Table 5 Relationship between CME morphometric parameters and BCVA/ EZA

From: Self-reported visual function and in-depth swept-source optical coherence tomography features of cystoid macular edema in retinitis pigmentosa

1) Retinal layers involvement

Anatomical structure or clinical feature

CS in INL

CS in INL + ONL

Z score* and p value

EZA (median, IQR) mm2

1.143 (0.518–3.104)

1.622 (0.474–2.920)

Z=-0.219

p = 0.826

BCVA (median, IQR) ETDRS letters

75 (65–85)

70 (65–80)

Z = 1.103

p = 0.271

2) CS size

Anatomical structure or clinical feature

Small and medium CS

Large and very large CS

Z score* and p value

EZA (median, IQR) mm2

1.143 (0.523–2.730)

1.840 (0.303–3.577)

Z=-0.621

p = 0.535

BCVA (median, IQR) ETDRS letters

75 (65–85)

70 (63–75)

Z = 1.375

p = 0.171

3) CS location

Anatomical structure or clinical feature

CS in CP

CS in CM and OCM

z score* and p value

CMT (mm), median (IQR)

0.449 (0.323–0.564)

0.269 (0.246–0.293)

Z=-3.969, p = 0.0008

EZA (mm2), median (IQR)

1.716 (0.758–4.051)

1.139 (0.518–2.871)

Z=-0.936, p = 0.347

BCVA, median (IQR)

70 (63–75)

81 (65–85)

Z = 2.192, p = 0.0285

4) CPONLT and CMT

Anatomical structure or clinical feature

Spearman correlation coefficient and p value

CPONLT

CMT

BCVA

EZA

r = 0.2034, p = 0.255

r = 0.0324 p = 0.847

r = 0.381 p = 0.0154

BCVA

r=-0.0824 p = 0.649

r=-0.402 p = 0.0112

NA

  1. *Mann-Whitney U test
  2. BCVA: best-corrected visual acuity; CS: cystoid spaces; CP: central point; CM: central millimeter; OCM: out of central millimeter; CMT: central macular thickness; INL: inner nuclear layer; ONL: outer nuclear layer; EZA: ellipsoid zone area; CPONLT: central point outer nuclear layer thickness; NA: not applicable