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Table 1 Demographics and baseline clinical characteristics by age at the diagnosis of VTDR

From: Is longer axial length protective of vision-threatening diabetic retinopathy across different ages? A multicenter cohort of 736 patients

 

Total (n = 736)

 ≤ 45 years (n = 144)

 > 45 years (n = 592)

P

Age, year

55.3 (48.0,64.0)

37.5 (33.0,42.0)

59.0 (54.0,65.0)

 < 0.001*

Male gender

424 (57.6)

94 (65.3)

330 (55.7)

0.038*

Duration of diabetes, year

15.1 (10,20)

10.0 (5.0,15.0)

16.0 (10.0,23.0)

 < 0.001*

College school or higher

64 (8.7)

42 (29.2)

22 (3.7)

 < 0.001*

Axial length, mm

23.34 (22.5,23.9)

23.9 (23.1,24.9)

23.0 (22.4,23.7)

 < 0.001*

Refractive Error, diopter

− 0.9 (− 0.5,0.0)

− 2.1 (− 4.0,0.0)

− 0.6 (0.0,0.0)

 < 0.001*

Type of diabetes

   

 <0.001*

 Type 1 diabetes

44 (6.0)

32 (22.2)

12 (2.0)

 

 Type 2 diabetes

692 (94.0)

112 (77.8)

580 (98.0)

 

HbAlc, %

7.7 (7.0,8.0)

7.6 (6.7,8.0)

7.7 (7.0,8.0)

0.092

SBP, mmHg

133.5 (122,143)

125.5 (115.0,140.0)

133.5 (124.0,145.0)

 < 0.001*

DBP, mmHg

79.6 (74.0,85.8)

81.7 (75.0,89.8)

79.1 (73.0,85.0)

 < 0.001*

LDL, mmol/L

2.7 (2.1,3.1)

2.7 (2.0,3.2)

2.8 (2.1,3.1)

0.867

BMI, kg/m2

24.2 (21.9,26.0)

24.8 (22.4,27.6)

23.9 (21.7,25.7)

 < 0.001*

With diabetic nephropathy

422 (57.3)

84 (58.3)

338 (57.1)

0.788

Current smoker

236 (32.1)

52 (36.1)

184 (31.1)

0.246

  1. Data are presented as median (interquartile range) or number (%)
  2. VTDR, vision-threatening diabetic retinopathy; SBP, systolic blood pressure; DBP, diastolic blood pressure; LDL, low density lipoprotein; BMI, body mass index
  3. *Statistically significant