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Table 2 Mean pre- and postoperative full-macular thickness measurements (in µm) obtained by OCT in patients and controls, divided into nine sectors, along with average thickness and macular volume, with corresponding values of areas under the ROC curve

From: Assessment of ganglion cell complex thickness and its correlation with retinal sensitivity using microperimetry 6 months after epiretinal membrane surgery

OCT full-macular thickness (µm)

Patients

(n = 43)

Controls (n = 43)

p-value

AUC

Fovea

    

 Pre-op 

455.4 ± 67.2

 

 < 0.001*

0.99 (0.98 – 1.00)

 Post-op 

373.5 ± 58.7

241.1 ± 34.3

 < 0.001*

0.96 (0.91 – 1.00)

 p-value

 < 0.001*

   

Temporal Inner

    

 Pre-op 

419.9 ± 58.1

 

 < 0.001*

0.99 (0.97 – 1.00)

 Post-op 

328.9 ± 56.8

298.1 ± 16.1

0.001*

0.73 (0.62 – 0.84)

 p-value

 < 0.001*

   

Superior inner

    

 Pre-op 

427.9 ± 54.1

 

 < 0.001*

0.99 (0.98 – 1.00)

 Post-op 

344.5 ± 35.1

309.8 ± 17.1

 < 0.001*

0.83 (0.75 – 0.92)

 p-value

 < 0.001*

   

Nasal Inner

    

 Pre-op 

410.7 ± 52.8

 

 < 0.001*

0.94 (0.89 – 1.00)

 Post-op 

358.5 ± 36.2

310.6 ± 17.9

 < 0.001*

0.89 (0.81 – 0.96)

 p-value

 < 0.001*

   

Inferior inner

    

 Pre-op 

397.1 ± 55.3

 

 < 0.001*

0.93 (0.88 – 0.99)

 Post-op 

334.7 ± 31.5

308.2 ± 20.5

 < 0.001*

0.76 (0.66 – 0.86)

 p-value

 < 0.001*

   

Temporal outer

    

 Pre-op 

312.5 ± 51.8

 

 < 0.001*

0.90 (0.83 – 0.98)

 Post-op

259.2 ± 27.1

254.4 ± 11.5

0.30

0.55 (0.43 – 0.68)

 p-value

 < 0.001*

   

Superior outer

    

 Pre-op 

327.0 ± 42.7

 

 < 0.001*

0.91 (0.84 – 0.98)

 Post-op 

279.0 ± 29.4

269.4 ± 14.6

0.06

0.64 (0.52 – 0.76)

 p-value

 < 0.001*

   

Nasal outer

    

 Pre-op 

328.4 ± 39.6

 

 < 0.001*

0.88 (0.80 – 0.95)

 Post-op

286.9 ± 26.9

284.5 ± 15.2

0.61

0.53 (0.41 – 0.66)

 p-value

 < 0.001*

   

Inferior outer

    

 Pre-op 

297.9 ± 45.5

 

 < 0.001*

0.76 (0.65 – 0.88)

 Post-op 

258.7 ± 24.7

259.8 ± 13.5

0.80

0.50 (0.38 – 0.63)

 p-value

 < 0.001*

   

Average thickness

    

 Pre-op 

342.8 ± 33.6

 

 < 0.001*

0.97 (0.92 – 1.00)

 Post-op

289.1 ± 23.1

275.1 ± 13.3

0.001*

0.71 (0.60 – 0.82)

 p-value

 < 0.001*

   

Macular volume

    

 Pre-op 

9.7 ± 0.9

 

 < 0.001*

0.97 (0.92 – 1.00)

 Post-op

8.2 ± 0.6

7.8 ± 0.4

0.001*

0.71 (0.60 – 0.82)

 p-value

 < 0.001*

   
  1. OCT: Optical coherence tomography; AUC: area under the ROC (receiver operating characteristic) curve; *: represents p < 0.05. by paired Student's t test (pre- versus post-surgery) and for independent samples (patients versus controls). pre-op: preoperative. post-op: postoperative