Fig. 2

Morphologic characteristics of foveal immaturity observed by use of spectral-domain optical coherence tomography (SD-OCT). The first line shows two phenotypes of cystoid macular edema; A, the presence of vertical edema and complete splitting of retinal layers without apparent foveal pit and B, the presence of cystic and vacuoles in retinal layers with foveal pitting. The second line illustrated a sample of foveal irregularity in ROP patients. The third line depicts samples for the presence or absence of Outer nuclear layer widening in ROP patients. The fourth and fifth lines are showing four classes of ONL widening: type A, ONL thickness increases from the periphery toward the fovea; type B, ONL thickness reduces or remains stable from the periphery toward the parafovea and then increases at the fovea; type C: no change in ONL thickness from the periphery toward foveal center, and type D, ONL thickness reduce from the periphery toward the fovea