Fig. 7
From: Pathomechanisms in central serous chorioretinopathy: A recent update
Effects of aldosterone injection in rat eyes. Control rat eyes (A, D) and aldosterone-injected rat eyes (B, C, E). Intravitreal injection of aldosterone in rat eyes in semi-thin sections shows (B) swollen Müller cells (arrows), thickened retinal pigment epithelial apical microvilli (stars), and thickened choroid (bidirectional arrows). Additionally, engorged choroidal vessels can be appreciated (C, star). Transmission electron microscopy (E) also shows an increased thickness of retinal pigment epithelial apical microvilli (arrows). INL, inner nuclear layer; IS/OS, inner and outer segments of photoreceptors. Bar: A and B, 20 μm; C, 10 μm; D and E, 2 μm. Reprinted with permission from Daruich et al. [5], under Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International (CC BY-NC-ND 4.0) License (https://creativecommons.org/licenses/by-nc-nd/4.0/legalcode)